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The McNamara Law Firm - Serving Santa Clarita, Valencia, Saugus, Castaic, Canyon Country, Newhall, Stevenson Ranch and surrounding communities. Our practice areas include Elder Law, Estate Planning, Wills and Living Trusts, Probate, Medi-Cal Planning, VA Benefits, and Trust Administration.

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  • Jane McNamara, Elder Law Attorney

Insulin Resistance and Alzheimer’s Disease


Back in 1906, Dr. Alois Alzheimer discovered that patients with cognitive decline had a certain protein in their brain called beta amyloid plaque. Since that time, the confirmed cases of Alzheimer’s disease has reached epidemic proportions. And still, there remains no cure.

Internationally recognized expert in neurodegenerative diseases, Dale Bredesen, MD, published a book in 2017 titled “The End of Alzheimer’s: The First Program to Prevent and Reverse Cognitive Decline.” In this book, Dr. Bredesen outlines many “factors” believed to cause Alzheimer’s, and how to prevent the disease. One major factor is that the amyloid plaque formation, which impairs cognition, is caused by a lack of insulin, or insulin resistance, in the brain.

The latest research connecting brain disease with insulin issues has led to Alzheimer’s now being referred to as type 3 diabetes. Again, this isn’t the ONLY cause or contributing factor, but it certainly is getting the attention of neurologists and researchers.

For many people, the problem starts with a diet high in sugar, carbohydrates, and processed foods. For others, it is how their body is wired. The cells in the body become weary of insulin asking the body to take excess glucose from the bloodstream, and after a while the cells quit listening to the insulin – they become insulin resistant. This ultimately causes damage to the brain, and is implicated in the formation of beta amyloid plaques, and Alzheimer’s.

Researchers are now saying that one way to combat this type of Alzheimer’s, or type 3 diabetes, may be to restore insulin sensitivity. Because there are few symptoms of insulin resistance (fatigue, belly fat, high blood pressure), you may not realize you have it.

My doctor, trained in Dr. Bredesen’s protocol, ordered several fasting blood tests. To my surprise (and his), my fasting glucose was consistently high, yet other blood “markers” were good. I don’t eat sugar, processed foods, or carb heavy foods. I exercise regularly, and have a proper body mass index. It appears I am insulin resistant, which can cause long term damage to my brain. We are now working on ways to restore insulin sensitivity, so that I am not an Alzheimer’s statistics in my later years. I am very thankful that we identified this issue, and taking action for my long-term brain health. Each and every person needs to understand the latest research, and take control of their health.

#insulinresistanceinsulin #AlzheimersPrevention

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